Goat Secondary Antibodies
Cayman Chemical 5-Aminothalidomide, Purity: ≥95%, CAS: 191732-76-0, 500 mg
A derivative of (±)-thalidomide; inhibits the proliferation of EA.hy926 endothelial cells (IC50 = 200 µM); an intermediate in the synthesis of a PROTAC c-MET degrader with antiproliferative activity in c-MET-sensitive cancer cells; an intermediate in the synthesis of a thalidomide derivative that reduces clinical scores in a mouse model of EAE
Cayman Chemical L-Arabinitol, Purity: ≥95%, CAS: 7643-75-6, 5 g
An endogenous metabolite; the ratio of D- to L-arabinitol in urine has been used as a marker of Candida infections
Cayman Chemical Allylthiourea, Purity: ≥95%, CAS: 109-57-9, 100 g
A nitritation inhibitor; inhibits nitritation in Nitrobacteriae by chelating the copper in the ammonia monooxygenase active site from 8-80 µM; has been used in the study of micropollutant degradation kinetics in soil
Cayman Chemical Amfenac (sodium salt hydrate), Purity: ≥98%, CAS: 61618-27-7, 1 g
A COX inhibitor (IC50s = 15.3 and 20.4 nM for the recombinant human COX-1 and COX-2, respectively) and the active metabolite of nepafenac; reduces the migration of 92.1 uveal melanoma cells at 150 nM, as well as proliferation of the same cells when used in combination with ranibizumab
Cayman Chemical 11-dehydro Thromboxane B2 Monoclonal Antibody, 100 dtn
11-dehydro Thromboxane B2 Monoclonal Antibody, 100 dtn
Cayman Chemical 4-Nitrodiphenylamine, Purity: ≥98%, CAS: 836-30-6, 1 g
An aromatic amine antioxidant; a component of both burnt gunshot residue and unburnt gunpowder
Cayman Chemical Octenidine (hydrochloride), Purity: ≥98%, CAS: 70775-75-6, 25 g
An antimicrobial agent; active against methicillin-sensitive and -resistant S. aureus, vancomycin-resistant Enterococcus, E. faecalis, S. pneumoniae, and C. albicans (MICs = 1-32 mg/L); reduces methicillin- or vancomycin-resistant S. aureus biofilm formation at 2 mM; reduces dental plaque accumulation in cynomolgus monkeys fed a high-sucrose diet at 1%
Cayman Chemical Pipemidic Acid (hydrate), Purity: ≥98%, CAS: 72571-82-5, 25 g
An antibiotic; active against clinical isolates of E. coli, P. mirabilis, P. inconstans, Shigella, Salmonella, Alcaligenes, and V. parahaemolyticus (MICs = 0.78-100 µg/ml), as well as drug-resistant clinical isolates of E. coli, P. mirabilis, Klebsiella, and Shigella (MICs = 1.56-6.25 µg/ml); Protective against systemic S. aureus, E. coli, K. pneumoniae, and P. aeruginosa infections in mice (ED50s = 237.5, 204.1, 28.6, and 99.5 mg/kg, respectively); protective against P. aeruginosa-induced pulmonary and dermal infections (ED50s = 81.7 and 173.2 mg/kg, respectively), as well as E. coli, K. pneumoniae, and P. aeruginosa urinary bladder infections (ED50s = 4.8, 11.9, and 30.6 mg/kg, respectively), in mice
Cayman Chemical DL-erythro/threo-Isocitric Acid (sodium salt hydrate), Purity: ≥95%, 5 g
A mixture of isocitric acid isomers
Cayman Chemical 6-Methylmercaptopurine, Purity: ≥95%, CAS: 50-66-8, 250 mg
A metabolite of 6-MP; formed from 6-MP via methylation by thiopurine S-methyltransferase; levels are increased in patients with altered thiopurine metabolism and associated with therapeutic resistance to 6-MP
Cayman Chemical β-Glucogallin, Purity: ≥98%, CAS: 13405-60-2, 250 mg
A plant metabolite and an aldose reductase 2 inhibitor (IC50 = 17 µM); inhibits glucose-induced sorbitol accumulation in lenses isolated from a transgenic mouse model overexpressing AKR1B1; reduces methylglyoxal-induced increases in COX-2, IL-6, IL-8, CCL2, and RAGE levels in ARPE-19 retinal epithelial cells
Cayman Chemical 3-hydroxy methyl Cefuroxime, Purity: ≥95%, CAS: 56271-94-4, 25 mg
A synthetic intermediate
Cayman Chemical Cytidine 5'-monophosphate, Purity: ≥95%, CAS: 63-37-6, 5 g
A pyrimidine nucleotide; used in the synthesis of RNA; an intermediate in the synthesis of phospholipids
Cayman Chemical Desvenlafaxine (succinate hydrate), Purity: ≥98%, CAS: 386750-22-7, 1 g
An active metabolite of venlafaxine; inhibits NET and SERT (IC50s = 47.3 and 531.3 nM, respectively); selective for NET and SERT over 50 non-transporter targets; increases extracellular NE in the male rat hypothalamus and 5-HT in the same region when used in combination with WAY-100635; reduces the time rats spend immobile in the forced swim test in a rat model of cognitive deficits and depression induced by MI when compared with MI-vehicle control animals 16 weeks following MI; improves learning in the passive avoidance step-down test two weeks following MI compared to MI-vehicle control rats and spatial memory in the Morris water maze 16 weeks following MI